Liver Cancer – Incidence, Symptoms, Causation, Diagnosis, Treatment and Prognosis
also known as liver cancer or primary liver cancer is relatively rare form of cancer in the Western world (1% of all cancers) but much more common in Africa and parts of Asia (10% to 50% of all cancers ). It 'much more common in men and incidence increases with age. This tumor is rapidly fatal, usually within 6 months from gastrointestinal hemorrhage, hepatic failure or metastasis.
Types of living CANCER
Most primary > Liver cancer tumors are known as hepatoma (primary liver cancer and less mobile). Some primary tumors originating in the bile duct, and these are known as cholangiomas. Some rare liver cancers include Kupffer cell sarcoma and hepatoblastomas (which occur almost exclusively in children and are usually respectable and curable). Metastasis is 20 times more common than primary liver cancer and cirrhosis after liver is the main form ofDeaths> Liver-related.
Signs and symptoms
This type of cancer usually do not cause symptoms until it is at an advanced stage.
Clinical effects of advanced liver cancers include:
A first mass in the upper right.
According to Tender, nodular liver on palpation
Third sharp pain in the stomach or upper right
Fourth weight loss, anorexia, fatigue, fever
Fifth occasional jaundice or ascites (fluid inAbdomen)
CAUSATION
The exact cause is unknown, but in adults, children may be a genetic disease. Carcinomas of the adult liver may result from exposure to environmental carcinogens such as mold contrast medium (no longer in use), androgens and estrogens oral hepatitis B or liver damage from alcohol-related cirrhosis also much more time to absorb through '.
DIAGNOSIS
It 'difficult to diagnose in the presence of cirrhosis, but some tests may Help identify: The combination of an imaging study (ultrasound, CT or MRI) and elevated blood levels of alpha-fetoprotein will effectively diagnose liver cancer most, studies of the liver may show an increase of electrolyte retention sodium, a biopsy, a definitive diagnosis.
TREATMENT
Treatments depend on the extent (stage) of disease, age, overall health, feelings and personal preferences. Surgery is the most effective treatment for primary> Cancer, but this is not always possible because of the size or location of the tumor. radiofrequency ablation is an option for people with small hepatocellular tumors unresectable and for certain types of metastatic liver cancer. During this procedure, the hepatic artery (the artery from which tumors arise Their blood supply) is blocked, and chemotherapy drugs Between the liver are injected block e. Cryoablation may be an option for people with inoperable primaryand metastatic liver cancer. Removing the whole liver and replacing it with another person's liver is another possible form of treatment for primary liver cancer.
Even when treatments fail to improve symptoms and to provide much of the tumor, pain and other symptoms caused can be treated aggressively to improve the quality of quality of life. In general, treatments are available for children than for adults, and the bestApproach depends on the stage and type of cancer and the child's age and general health.
PROGNOSIS
The prognosis is poor when cancer is advanced, but for small tumors, the liver will be limited to, the ablative therapy and palliative resection or liver transplantation is sometimes curative.
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